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Oxycodone

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Oxycodone is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.

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Product Description

Oxycodone is a potent, semi-synthetic opioid pain medication prescribed to manage severe, chronic, or acute pain when other treatments are insufficient. As a central nervous system depressant, it alters how the brain and nervous system respond to pain.

Common Forms and Brands

Oxycodone is available in various oral formulations and is frequently combined with other non-opioid medications: [1, 2]

- Immediate-Release (IR): Taken every 4 to 6 hours for breakthrough or sudden pain. Examples include Roxicodone and Oxy-IR.
- Extended-Release (ER) / Controlled-Release (CR): Taken every 12 hours for around-the-clock pain management. Examples include OxyNEO, and older, discontinued formulations like OxyContin.

Combination Drugs: Blended with acetaminophen (e.g., Percocet or Endocet) or aspirin (Percodan). [1, 2, 3, 4, 5]

Risks and Side Effects

Due to its high potential for abuse, addiction, and dependence, oxycodone is classified as a Schedule II controlled substance. Common side effects include: [1, 2]

Constipation, nausea, and vomiting
Drowsiness, dizziness, and headacheDry mouth and sweating [1
Critical Safety Warnings:
- Overdose Risk: Crushing, chewing, or dissolving extended-release tablets releases a potentially fatal dose of the medication all at once. [1]
- Respiratory Depression: Combining oxycodone with alcohol or other central nervous system depressants (like benzodiazepines) can slow or stop breathing entirely. [1, 2, 3, 4]
- Withdrawal: Stopping the medication abruptly after long-term use can cause severe withdrawal symptoms.

Oxycodone side effects at a glance

Like all opioids, oxycodone has possible side effects to be aware of. Mild side effects can usually be managed at home. But more serious side effects might need medical attention.

Common, and usually mild, side effects: